Description

(5R)-5,6,7,8-Tetrahydro-4-Hydroxy-8β-[(1S,4E)-6-Hydroxy-1,5-Dimethyl-4-Hexenyl]-5α-Methyl-2-Naphthalenecarboxylic Acid CAS NO 65003-68-1 is a complex, high-purity synthetic intermediate with a defined stereochemistry. This compound is of significant interest for its role as a key building block in advanced pharmaceutical synthesis, particularly for the development of novel therapeutic agents. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, particularly in steroid-like or complex polycyclic frameworks.
• Organic Synthesis Research: Used as a sophisticated building block in academic and industrial research for constructing complex natural product analogs.
• Process Chemistry Development: Serves as a key material for scaling up synthetic routes in pilot plants and optimizing manufacturing processes for active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Biochemical Research: Potential use in studying enzyme interactions or as a probe molecule due to its specific stereochemical configuration.

Basic Information

Item	Details
Product Name	(5R)-5,6,7,8-Tetrahydro-4-Hydroxy-8β-[(1S,4E)-6-Hydroxy-1,5-Dimethyl-4-Hexenyl]-5α-Methyl-2-Naphthalenecarboxylic Acid
CAS No.	65003-68-1
Molecular Formula	C₂₀H₂₈O₄
Molecular Weight	332.43 g/mol
Synonyms	4-Hydroxy-8β-[(1S,4E)-6-hydroxy-1,5-dimethyl-4-hexen-1-yl]-5α-methyl-5,6,7,8-tetrahydro-2-naphthoic acid; (5R,8β,5α)-5,6,7,8-Tetrahydro-4-hydroxy-8-[(1S,4E)-6-hydroxy-1,5-dimethyl-4-hexenyl]-5-methyl-2-naphthalenecarboxylic acid; A key intermediate for Vitamin D analogs; Tetrahydro naphthalene carboxylic acid derivative.
EINECS	Contact for details

Quality Control

Our (5R)-5,6,7,8-Tetrahydro-4-Hydroxy-8β-[(1S,4E)-6-Hydroxy-1,5-Dimethyl-4-Hexenyl]-5α-Methyl-2-Naphthalenecarboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to ensure full traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.