Description

8-Chloro-4-Ethoxyquinoline is a versatile quinoline derivative that serves as a critical synthetic intermediate and building block in advanced organic chemistry. Its unique halogenated and alkoxylated structure makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or central nervous system disorders.
• Agrochemical Research: Used in developing new pesticides, herbicides, and fungicides due to the bioactive quinoline core.
• Organic Synthesis Reagent: Serves as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the quinoline moiety.
• Material Science Precursor: Employed in the development of organic semiconductors, light-emitting materials, and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	8-Chloro-4-Ethoxyquinoline
CAS No.	64965-29-3
Molecular Formula	C₁₁H₁₀ClNO
Molecular Weight	207.66 g/mol
Synonyms	8-Chloro-4-ethoxyquinoline; 4-Ethoxy-8-chloroquinoline; Quinoline, 8-chloro-4-ethoxy-; 8-Chloro-4-ethoxy-quinoline; 64965-29-3
EINECS	Contact for details

Quality Control

Our 8-Chloro-4-Ethoxyquinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC chromatograms and NMR spectra, to verify identity and purity. Certificates of Analysis (COA) are available for every batch and provided upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.