Description

2-Chloro-1-(4-Ethoxyphenyl)Ethanone is a versatile organic building block and key intermediate in fine chemical synthesis. Its value lies in the reactive chloroketone and ethoxyphenyl functional groups, which enable its use in constructing more complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those containing aryl ketone or phenethylamine backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where the ethoxyphenyl moiety is a desired structural component.
• Organic Synthesis Building Block: Serves as a versatile electrophile in Friedel-Crafts alkylation, nucleophilic substitution, and reductive amination reactions to introduce functionalized side chains.
• Ligand and Catalyst Development: Employed in research for the preparation of novel chelating ligands or organocatalysts for asymmetric synthesis.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of certain azo dyes and organic pigments due to its ketone functionality which can be further derivatized.

Basic Information

Product Name	2-Chloro-1-(4-Ethoxyphenyl)Ethanone
CAS No.	64953-82-8
Molecular Formula	C10H11ClO2
Molecular Weight	198.65 g/mol
Synonyms	4'-Ethoxy-2-chloroacetophenone; 2-Chloro-1-(4-ethoxyphenyl)ethan-1-one; 1-(4-Ethoxyphenyl)-2-chloroethanone; p-Ethoxyphenacyl Chloride; 4-Ethoxy-α-chloroacetophenone; 2-Chloro-4'-ethoxyacetophenone; α-Chloro-4-ethoxyacetophenone; NSC 403914
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(4-Ethoxyphenyl)Ethanone is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.