Description

7-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core naphthyridinone scaffold, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for creating organic semiconductors, ligands for catalysis, and specialty polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig couplings to introduce diverse functionalities.

Basic Information

Product Name	7-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one
CAS No.	64942-87-6
Molecular Formula	C8H7BrN2O
Molecular Weight	227.06 g/mol
Synonyms	7-Bromo-1,2,3,4-tetrahydro-1,8-naphthyridin-4-one; 7-Bromo-3,4-dihydro-1H-1,8-naphthyridin-4-one; 4(1H)-One, 7-bromo-2,3-dihydro-1,8-naphthyridin-; 7-Bromo-1,2,3,4-tetrahydro-1,8-naphthyridin-4-one; 7-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one; 7-Bromotetrahydro-1,8-naphthyridin-4-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-2,3-dihydro-1,8-naphthyridin-4(1H)-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.