Description

(Z)-2-Methyl-2-Butenoic Acid [(3As)-2,3,3A,4,4A,5,7Aα,8,9,9Aα-Decahydro-4Aβ,8α-Dimethyl-3-Methylene-2,5,9-Trioxoazuleno[6,5-B]Furan-4α-Yl] Ester is a specialized, high-purity synthetic intermediate characterized by its complex, fused-ring structure. This compound is valued for its role as a key chiral building block in advanced organic synthesis, enabling the construction of intricate molecular architectures. It is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs) and complex natural product analogs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex, biologically active molecules and potential new chemical entities (NCEs).
• Advanced Organic Synthesis: Used as a chiral scaffold or building block for constructing polycyclic frameworks in medicinal chemistry and total synthesis projects.
• Chemical Research & Development: Employed in academic and industrial R&D settings for exploring new synthetic methodologies and reaction pathways.
• Specialty Fine Chemicals: Applicable in the production of high-value, low-volume specialty chemicals for research and niche industrial applications.

Basic Information

Product Name	(Z)-2-Methyl-2-Butenoic Acid [(3As)-2,3,3A,4,4A,5,7Aα,8,9,9Aα-Decahydro-4Aβ,8α-Dimethyl-3-Methylene-2,5,9-Trioxoazuleno[6,5-B]Furan-4α-Yl] Ester
CAS No.	64937-26-4
Molecular Formula	C₂₁H₂₄O₆
Molecular Weight	372.41 g/mol
Synonyms	(Z)-2-Methylbut-2-enoic acid (3aR,4aR,7aS,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-4a,8-dimethyl-3-methylene-2,5,9-trioxoazuleno[6,5-b]furan-4-yl ester; Tiglic Acid Azuleno[6,5-b]furan Ester; (Z)-Tiglic Acid Ester of a Decahydroazulenofurantrione Derivative; 64937-26-4; Azuleno[6,5-b]furan-4(4aH)-one, 2,3,3a,4,4a,5,7a,8,9,9a-decahydro-4a,8-dimethyl-3-methylene-2,5,9-trioxo-, (Z)-2-methyl-2-butenoate; A complex sesquiterpenoid lactone derivative ester.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency and high purity. Identity and purity are confirmed through a suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.