Description

3-[p-(9-Acridinylamino)Phenyl]Propenoic Acid is a specialized acridine derivative known for its unique photophysical and biochemical properties. This compound matters as a high-value intermediate and research chemical, particularly valued for its potential in developing fluorescent probes and targeted therapeutic agents. It is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers working in areas such as photodynamic therapy, DNA intercalation studies, and advanced material science. The product is supplied with a focus on purity and batch-to-batch consistency to meet rigorous research and development requirements.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active moiety in the synthesis of novel therapeutic agents, particularly for investigating anti-cancer and antimicrobial applications.
• Biochemical Probes & Assays: Utilized in the development of fluorescent probes for studying biomolecular interactions, enzyme activity, and cellular imaging due to its acridine-based chromophore.
• Photodynamic Therapy (PDT) Research: Investigated as a potential photosensitizer precursor for cancer treatment, leveraging its ability to generate reactive oxygen species upon light activation.
• DNA/RNA Intercalation Studies: Applied in biochemical research to study binding interactions with nucleic acids, useful for understanding mechanisms of certain drugs and designing new ones.
• Material Science: Used in the synthesis of organic semiconductors, light-emitting materials, or other advanced functional materials where its conjugated structure is beneficial.
• Analytical Chemistry: May serve as a standard or reagent in chromatographic methods or spectroscopic analysis for quality control in related chemical syntheses.

Basic Information

Product Name	3-[p-(9-Acridinylamino)Phenyl]Propenoic Acid
CAS No.	64895-08-5
Molecular Formula	C22H16N2O2
Molecular Weight	340.38 g/mol
Synonyms	3-[4-(9-Acridinylamino)phenyl]-2-propenoic acid; (E)-3-[4-(Acridin-9-ylamino)phenyl]acrylic acid; 9-[[4-(2-Carboxyethenyl)phenyl]amino]acridine; Acridine Yellow G analogue; APPA; NSC 338720; p-(9-Acridinylamino)cinnamic acid; trans-3-[p-(9-Acridinylamino)phenyl]acrylic acid
EINECS	Contact for details

Quality Control

Our 3-[p-(9-Acridinylamino)Phenyl]Propenoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific batch results are available upon request. We can support development projects by providing material that aligns with early-stage research or GMP-grade requirements, subject to specific inquiry.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store under dry, inert conditions (e.g., nitrogen atmosphere) for long-term preservation. Recommended storage temperature is 2-8°C for optimal stability. Keep the container in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.