Description

6-Chloro-1,8-Naphthyridin-2-Amine is a high-value, nitrogen-containing heterocyclic building block with significant synthetic utility. This compound matters as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition, antimicrobial activity, or anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a building block for creating organic ligands in catalysis or for developing novel organic electronic materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and target identification.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO (Contract Research Organization) laboratories.
• Custom Synthesis & Scale-up: A critical starting material for custom manufacturing and process optimization for commercial-scale production of specialty chemicals.

Basic Information

Product Name	6-Chloro-1,8-Naphthyridin-2-Amine
CAS No.	64874-37-9
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	2-Amino-6-chloro-1,8-naphthyridine; 6-Chloro-1,8-naphthyridin-2-amine; 6-Chloro-2-amino-1,8-naphthyridine; 1,8-Naphthyridine, 6-chloro-2-amino-; 2-Amino-6-chloro[1,8]naphthyridine; 6-Chloro-2-aminonaphthyridine; 6-Chloro-1,8-naphthyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our 6-Chloro-1,8-Naphthyridin-2-Amine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.