Description

(3R,3'Ar,5S,6'Aβ,10'Ar)-4,5,4',5',6',6'A,9',10'-Octahydro-5-(3-Furyl)-10'β-Hydroxy-8'α-Methylspiro[Furan-3(2H),7'(8'H)-Naphtho[1,8A-C]Furan]-2,3'(3'Ah)-Dione is a complex, high-purity spirocyclic furan derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated chiral building block and a key intermediate for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create molecules with specific stereochemical and functional properties.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used as a building block for developing novel pesticides and herbicides with enhanced efficacy and selectivity.
• Asymmetric Synthesis: Employed as a key starting material or intermediate in catalytic asymmetric reactions to construct stereochemically defined molecular architectures.
• Fine Chemical Production: Serves in the manufacture of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic chemistry and for studying complex reaction mechanisms.
• Material Science Precursor: Potential use in synthesizing organic electronic materials or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	(3R,3'Ar,5S,6'Aβ,10'Ar)-4,5,4',5',6',6'A,9',10'-Octahydro-5-(3-Furyl)-10'β-Hydroxy-8'α-Methylspiro[Furan-3(2H),7'(8'H)-Naphtho[1,8A-C]Furan]-2,3'(3'Ah)-Dione
CAS No.	64719-81-9
Molecular Formula	C23H24O6
Molecular Weight	396.43 g/mol
Synonyms	8α-Methyl-10β-hydroxy-5-(3-furyl)spiro[furan-3(2H),7'(8'H)-naphtho[1,8a-c]furan]-2,3'(3'aH)-dione; Spiro[furan-3(2H),7'(8'H)-naphtho[1,8a-c]furan]-2,3'(3'aH)-dione, 4,5,4',5',6',6'a,9',10'-octahydro-5-(3-furanyl)-10'β-hydroxy-8'α-methyl-, (3R,3'aR,5S,6'aS,10'aR)-; 64719-81-9; Spirocyclic Furan Dione Derivative; Chiral Spiro Furanone
EINECS	Contact for details

Quality Control

Our (3R,3'Ar,5S,6'Aβ,10'Ar)-4,5,4',5',6',6'A,9',10'-Octahydro-5-(3-Furyl)-10'β-Hydroxy-8'α-Methylspiro[Furan-3(2H),7'(8'H)-Naphtho[1,8A-C]Furan]-2,3'(3'Ah)-Dione is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting research and pharmaceutical-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to light and oxidation, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.