Description

D-Proline, 1-Nitro- (9Ci) is a specialized, non-proteinogenic amino acid derivative characterized by its D-configuration and a nitro substituent on the proline ring. This unique chiral building block is critical for advanced organic synthesis and pharmaceutical research, enabling the creation of novel compounds with specific stereochemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as peptidomimetics and catalyst development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptidomimetic drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Research: Used in the synthesis of novel, biologically active compounds for crop protection and pest management.
• Peptide Chemistry: Incorporated into modified peptide sequences to study structure-activity relationships and enhance metabolic stability.
• Fine Chemical Production: Acts as a building block for the manufacture of complex, high-value specialty chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry at universities and corporate R&D centers.

Basic Information

Item	Details
Product Name	D-Proline, 1-Nitro- (9Ci)
CAS No.	64693-50-1
Molecular Formula	C5H8N2O4
Molecular Weight	160.13 g/mol
Synonyms	(2R)-1-Nitropyrrolidine-2-carboxylic acid; D-1-Nitropyrrolidine-2-carboxylic acid; (R)-1-Nitropyrrolidine-2-carboxylic acid; D-1-Nitroproline; (R)-1-Nitroproline; 1-Nitro-D-proline; (R)-1-Nitropyrrolidine-2-carboxylic Acid; 64693-50-1
EINECS	Contact for details

Quality Control

Every batch of D-Proline, 1-Nitro- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and synthesis. A detailed Certificate of Analysis (COA) is available for each lot, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Optical Rotation	Specific range provided on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.