Description

L-Proline, 1-Nitro- (9Ci) CAS NO 64693-49-8 is a specialized, non-proteinogenic amino acid derivative characterized by the introduction of a nitro group at the 1-position of the L-proline ring. This modification makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for constructing complex molecules with defined stereochemistry. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active compounds and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for peptidomimetics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of novel, biologically active molecules for crop protection and pest management research.
• Fine Chemical Production: Acts as a building block for synthesizing specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Biochemical Research: Employed in studies of amino acid metabolism, enzyme-substrate interactions, and the design of modified peptides.
• Material Science: Investigated as a precursor for functionalized polymers or organic frameworks with specific chiral properties.

Basic Information

Item	Details
Product Name	L-Proline, 1-Nitro- (9Ci)
CAS No.	64693-49-8
Molecular Formula	C5H8N2O4
Molecular Weight	160.13 g/mol
Synonyms	(2S)-1-Nitropyrrolidine-2-carboxylic acid; 1-Nitro-L-proline; L-1-Nitropyrrolidine-2-carboxylic acid; (S)-1-Nitropyrrolidine-2-carboxylic acid; 1-Nitroproline; Nitroproline; 64693-49-8
EINECS	Contact for details

Quality Control

Our L-Proline, 1-Nitro- (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, documenting key parameters such as assay, chiral purity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring specific quality grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.