Description

2-Bromo-4-Chloroquinoline is a versatile halogenated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its dual halogen functionality, which provides distinct reactive sites for selective cross-coupling and substitution reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of quinoline-based drug candidates, including potential antimicrobials, anticancer agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline core contributes to biological activity.
• Material Science Research: Employed in the development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Catalyst Ligand Precursor: Utilized to synthesize novel nitrogen-containing ligands for transition metal catalysis.
• Fine Chemical Production: Acts as a precursor for other specialty chemicals and dyes.

Basic Information

Product Name	2-Bromo-4-Chloroquinoline
CAS No.	64658-05-5
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	4-Chloro-2-bromoquinoline; 2-Bromo-4-chloroquinoline; Quinoline, 2-bromo-4-chloro-; 64658-05-5; 2-Bromo-4-chloro-quinoline; 4-Chloro-2-bromo-quinoline
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloroquinoline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide detailed Certificates of Analysis (COA) with every shipment, documenting identity, purity, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat sources and incompatible materials. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.