Description

7-Trifluoromethyl-4-Quinolinethiol CAS NO 64415-07-2 is a high-value, sulfur-containing heterocyclic building block characterized by its quinoline core and trifluoromethyl substituent. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and the creation of specialized ligands and catalysts.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially for targets in oncology, infectious diseases, and central nervous system disorders.
• Agrochemical Research: Used in developing new active ingredients for herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline-thiol moiety.
• Material Science: Serves as a building block for organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Synthesis: Acts as a versatile reagent for introducing the trifluoromethylquinoline scaffold into more complex molecules via coupling reactions.
• Catalyst & Ligand Development: Utilized in the design of novel ligands for transition metal catalysis due to the coordinating ability of the thiol group.
• Analytical Reference Standard: Employed as a certified reference material (CRM) in quality control and analytical method development for related compounds.

Basic Information

Product Name	7-Trifluoromethyl-4-Quinolinethiol
CAS No.	64415-07-2
Molecular Formula	C10H6F3NS
Molecular Weight	229.22 g/mol
Synonyms	4-Quinolinethiol, 7-(trifluoromethyl)-; 7-(Trifluoromethyl)-4-quinolinethiol; 7-Trifluoromethylquinoline-4-thiol; 4-Mercapto-7-trifluoromethylquinoline; 7-Trifluoromethyl-4-mercaptoquinoline; 4-Thiol-7-trifluoromethylquinoline; 64415-07-2; 7-Trifluoromethyl-4-quinolinetiol
EINECS	Contact for details

Quality Control

Our 7-Trifluoromethyl-4-Quinolinethiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.