Description

1-Oxo-1H-Pyrimido[1,2-A]Quinoline-2-Carboxylic Acid is a high-purity, specialized heterocyclic carboxylic acid building block of significant interest in advanced organic synthesis. Its unique fused pyrimidoquinoline core structure makes it a valuable intermediate for developing novel pharmacologically active compounds and functional materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its complex heterocyclic scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in advanced display technologies.
• Coordination Chemistry & Ligand Synthesis: The carboxylic acid and nitrogen-containing heterocycle can act as a chelating ligand for metal complexes used in catalysis or sensing.
• Dye & Pigment Chemistry: Employed in the synthesis of specialized heterocyclic dyes and pigments due to its extended conjugated system.
• Academic & Contract Research: A critical reagent for methodological studies in organic synthesis and medicinal chemistry within university and CRO laboratories.

Basic Information

Product Name	1-Oxo-1H-Pyrimido[1,2-A]Quinoline-2-Carboxylic Acid
CAS No.	64399-31-1
Molecular Formula	C₁₄H₈N₂O₃
Molecular Weight	252.23 g/mol
Synonyms	Pyrimido[1,2-a]quinoline-2-carboxylic acid, 1-oxo-; 1-Oxo-1H-pyrimido[1,2-a]quinoline-2-carboxylic acid; 1H-Pyrimido[1,2-a]quinoline-2-carboxylic acid, 1-oxo-; Quinoline-2-carboxylic acid, 1-oxo-1H-pyrimido[1,2-a]-; 64399-31-1; UNII-8V4A3N6OAZ; 8V4A3N6OAZ
EINECS	Contact for details

Quality Control

Every batch of 1-Oxo-1H-Pyrimido[1,2-A]Quinoline-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and mass spectrometry confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.