Description

Methyl 2,3,5-Tri-o-Benzyl-D-Ribofuranoside is a key protected ribofuranoside derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its primary value lies in providing a versatile, benzyl-protected ribose scaffold that is essential for constructing complex nucleoside analogs and other bioactive molecules. This high-purity intermediate is indispensable for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors, particularly for the development of antiviral agents, nucleotide-based therapeutics, and specialty carbohydrates.

Application

• Nucleoside & Nucleotide Synthesis: A fundamental precursor for the preparation of modified nucleosides and nucleotides used in antiviral and anticancer drug discovery.
• Pharmaceutical Intermediates: Serves as a chiral synthon in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), especially those targeting RNA viruses.
• Carbohydrate Chemistry: Used in the synthesis of complex oligosaccharides, glycoconjugates, and other sugar-derived compounds for biochemical research.
• Prodrug Development: Employed in the design and synthesis of prodrugs where a protected sugar moiety is required for targeted delivery or metabolic stability.
• Bioconjugation & Labeling: Acts as a starting material for creating labeled nucleotides or carbohydrate probes used in diagnostic assays and molecular biology.
• Fine Chemical & Catalyst Research: Utilized in asymmetric synthesis and as a ligand precursor in the development of chiral catalysts.

Basic Information

Item	Details
Product Name	Methyl 2,3,5-Tri-o-Benzyl-D-Ribofuranoside
CAS No.	64363-77-5
Molecular Formula	C27H30O5
Molecular Weight	434.52 g/mol
Synonyms	Methyl 2,3,5-Tri-O-benzyl-D-ribofuranoside; 1-O-Methyl-2,3,5-tri-O-benzyl-D-ribofuranose; D-Ribofuranoside, methyl 2,3,5-tris-O-(phenylmethyl)-; Methyl 2,3,5-Tri-O-benzyl-β-D-ribofuranoside; 2,3,5-Tri-O-benzyl-1-O-methyl-D-ribofuranose; Methyl 2,3,5-Tri-O-benzylribofuranoside; Protected Methyl Ribofuranoside
EINECS	Contact for details

Quality Control

Our Methyl 2,3,5-Tri-o-Benzyl-D-Ribofuranoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the stringent requirements for synthetic intermediates. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and identity is provided with every shipment to guarantee traceability and consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% (D-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.