Description

(E)-3-(4-Chlorophenylsulfonyl)Acrylonitrile is a versatile and high-value organic intermediate characterized by its unique sulfonyl acrylonitrile structure. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or receptor modulators.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its reactive acrylonitrile moiety.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with tailored properties like thermal stability or specific reactivity.
• Organic Synthesis Building Block: Employed in Michael addition reactions, cycloadditions, and other C-C bond-forming transformations to create complex molecular architectures.
• Bioconjugation Chemistry: Potential use in modifying biomolecules due to the electrophilic nature of the acrylonitrile group, useful for probe or linker attachment.

Basic Information

Product Name	(E)-3-(4-Chlorophenylsulfonyl)Acrylonitrile
CAS No.	64326-48-3
Molecular Formula	C9H6ClNO2S
Molecular Weight	227.67 g/mol
Synonyms	(E)-3-[(4-Chlorophenyl)sulfonyl]-2-propenenitrile; 3-[(4-Chlorophenyl)sulfonyl]acrylonitrile; 2-Propenenitrile, 3-[(4-chlorophenyl)sulfonyl]-, (E)-; 4-Chlorophenyl vinyl sulfone cyanide; (E)-3-(p-Chlorophenylsulfonyl)acrylonitrile; trans-3-(4-Chlorobenzenesulfonyl)acrylonitrile; p-Chlorophenylsulfonylacrylonitrile
EINECS	Contact for details

Quality Control

Our (E)-3-(4-Chlorophenylsulfonyl)Acrylonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.