Description

(E)-3-(Phenylsulfonyl)Acrylonitrile is a versatile and high-value organic building block characterized by its conjugated electron-withdrawing sulfone and nitrile functionalities. This compound is essential for facilitating advanced carbon-carbon and carbon-heteroatom bond-forming reactions in complex synthetic pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of biologically active molecules, including kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its reactive acrylonitrile moiety.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Organic Synthesis Building Block: Employed in Michael additions, cycloadditions, and other conjugate addition reactions to introduce sulfone and nitrile groups.
• Ligand and Catalyst Development: Useful for constructing novel chelating ligands and organocatalysts for asymmetric synthesis.
• Dye and Pigment Intermediate: Acts as a precursor in the synthesis of specialized chromophores and functional dyes.

Basic Information

Product Name	(E)-3-(Phenylsulfonyl)Acrylonitrile
CAS No.	64326-47-2
Molecular Formula	C9H7NO2S
Molecular Weight	193.22 g/mol
Synonyms	(E)-3-(Benzenesulfonyl)acrylonitrile; trans-3-(Phenylsulfonyl)acrylonitrile; 2-Propenenitrile, 3-(phenylsulfonyl)-, (2E)-; 3-(Phenylsulfonyl)-2-propenenitrile; (E)-3-(Phenylsulfonyl)propenenitrile; NSC 339063; (E)-β-(Phenylsulfonyl)acrylonitrile
EINECS	Contact for details

Quality Control

Our (E)-3-(Phenylsulfonyl)Acrylonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the exacting standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.