Description

2-Propenamide, 3-(1H-Indol-3-Yl)-n-(1-Methylethyl)- is a specialized acrylamide derivative featuring an indole moiety and an isopropyl substituent on the nitrogen. This unique molecular structure makes it a valuable advanced intermediate for the synthesis of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, where its reactive acrylamide group enables further functionalization.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of potential drug candidates, especially those targeting neurological or oncological pathways.
• Agrochemical Research: Used in developing novel pesticides, herbicides, or plant growth regulators that leverage the indole scaffold.
• Bioconjugation & Probe Synthesis: The acrylamide group can be utilized for Michael addition reactions to create fluorescent probes or protein conjugates for biochemical studies.
• Polymer Science R&D: Serves as a functional monomer for creating specialty polymers with unique thermal or optical properties derived from the indole unit.
• Academic & Contract Research: Essential for synthetic organic chemistry research in universities and CROs exploring new heterocyclic compounds and reaction methodologies.

Basic Information

Product Name	2-Propenamide, 3-(1H-Indol-3-Yl)-n-(1-Methylethyl)-
CAS No.	64319-77-3
Molecular Formula	C₁₄H₁₆N₂O
Molecular Weight	228.29 g/mol
Synonyms	N-Isopropyl-3-(1H-indol-3-yl)acrylamide; 3-(1H-Indol-3-yl)-N-isopropylacrylamide; N-Isopropyl-3-indol-3-yl-acrylamide; 3-(Indol-3-yl)-N-isopropylpropenamide; (E)-N-Isopropyl-3-(1H-indol-3-yl)acrylamide; Acrylamide, N-isopropyl-3-(3-indolyl)-; 3-(1H-Indol-3-yl)-N-(propan-2-yl)prop-2-enamide
EINECS	Contact for details

Quality Control

Every batch of 2-Propenamide, 3-(1H-Indol-3-Yl)-n-(1-Methylethyl)- is produced and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards for research-grade chemicals. Standard analytical techniques including HPLC, NMR, and mass spectrometry are employed to verify identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.