Description

(R)-(+)-1-(4-Bromophenyl)Ethylamine Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a key synthon for the asymmetric synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals, where the specific (R)-enantiomer is often critical for biological activity. This compound is essential for research and production in pharmaceutical development, particularly for creating molecules with targeted therapeutic effects, and is sought after by fine chemical manufacturers and R&D laboratories globally.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of novel APIs, especially in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a chiral amine source or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block for developing advanced, enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Fine Chemical Production: Integrated into multi-step synthesis processes for high-value specialty chemicals and performance materials.

Basic Information

Product Name	(R)-(+)-1-(4-Bromophenyl)Ethylamine Hydrochloride
CAS No.	64265-77-6
Molecular Formula	C8H10BrN • HCl
Molecular Weight	236.53 g/mol (Free base: 200.08 g/mol)
Synonyms	(R)-(+)-1-(4-Bromophenyl)ethylamine HCl; (R)-1-(4-Bromophenyl)ethanamine hydrochloride; (R)-α-Methyl-4-bromobenzylamine hydrochloride; (R)-4'-Bromo-α-methylbenzylamine hydrochloride; (R)-1-(p-Bromophenyl)ethylamine hydrochloride; Dextro-1-(4-Bromophenyl)ethylamine hydrochloride; (R)-(+)-p-Bromo-α-methylbenzylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(4-Bromophenyl)Ethylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.