Description

Z-D-Tyr-Oh CAS NO 64205-12-5 is a protected derivative of the amino acid tyrosine, specifically the Z-protected D-enantiomer. This compound is a critical chiral building block in the synthesis of complex peptides and peptidomimetics, where it provides precise stereochemical control. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-tyrosine residues with orthogonal protection.
• Biochemical Research: Employed in the study of enzyme-substrate interactions, receptor binding, and the structure-activity relationships (SAR) of peptides.
• Proteomics & Diagnostics: Serves as a building block for labeled peptides used in mass spectrometry, assay development, and diagnostic probe synthesis.
• Academic & R&D Laboratories: A fundamental reagent for synthetic organic chemistry and medicinal chemistry research projects.

Basic Information

Product Name	Z-D-Tyr-Oh
CAS No.	64205-12-5
Molecular Formula	C17H17NO5
Molecular Weight	315.32 g/mol
Synonyms	N-Carbobenzoxy-D-tyrosine; Z-D-Tyrosine; (R)-2-((((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid; D-Tyrosine, N-[(phenylmethoxy)carbonyl]-; CBZ-D-Tyrosine; Nα-Cbz-D-tyrosine; N-CBZ-D-Tyrosine; Benzyloxycarbonyl-D-tyrosine
EINECS	Contact for details

Quality Control

Our Z-D-Tyr-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.