Description

2-Phenyl-4-(Trifluoromethyl)Quinoline is a high-value, fluorinated quinoline derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a phenyl group and a trifluoromethyl substituent, imparts specific electronic and steric properties essential for developing novel functional materials and active pharmaceutical ingredients. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and materials science industries for creating next-generation products with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for targets requiring fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, where the quinoline core and fluorine atoms can contribute to improved efficacy and environmental profile.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor or core structure for electron-transport materials or host materials in OLED devices due to its rigid, conjugated system.
• Ligand in Catalysis: Serves as a scaffold for developing specialized ligands in transition metal catalysis for asymmetric synthesis and cross-coupling reactions.
• Fluorescent Probe Development: Utilized in academic and industrial research to create fluorescent dyes and sensors for biological imaging or chemical detection.
• Material Science: Incorporated into polymers or small molecules to study structure-property relationships for electronic or optical applications.

Basic Information

Product Name	2-Phenyl-4-(Trifluoromethyl)Quinoline
CAS No.	64196-43-6
Molecular Formula	C₁₆H₁₀F₃N
Molecular Weight	273.25 g/mol
Synonyms	4-(Trifluoromethyl)-2-phenylquinoline; 2-Phenyl-4-trifluoromethylquinoline; Quinoline, 2-phenyl-4-(trifluoromethyl)-; 4-Trifluoromethyl-2-phenylquinoline; 2-Phenyl-4-(trifluoromethyl)quinoline; α-Phenyl-4-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 2-Phenyl-4-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to strong alkali and fluoride sources; appropriate chemical segregation practices should be followed.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.