Description

Spiro[1-Azabicyclo[2.2.2]Octane-3,2'-Oxirane] Hydrochloride is a high-purity, complex heterocyclic building block of significant interest in advanced organic synthesis. Its unique spirocyclic and bridged bicyclic architecture makes it a critical intermediate for constructing sophisticated molecular frameworks with precise three-dimensional control. This compound is primarily sought after by pharmaceutical R&D and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in neurological and therapeutic areas.
• Advanced Organic Synthesis: Used as a versatile building block for constructing complex spirocyclic and bridged nitrogen-containing heterocycles.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Employed in the synthesis of novel bioactive molecules for crop protection and agricultural chemistry.
• Material Science: Potential monomer or additive for developing specialty polymers with unique structural properties.
• Academic & Institutional Research: A valuable compound for methodological studies in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	Spiro[1-Azabicyclo[2.2.2]Octane-3,2'-Oxirane] Hydrochloride
CAS No.	64168-68-9
Molecular Formula	C9H14ClNO2
Molecular Weight	203.67 g/mol
Synonyms	1-Azaspiro[bicyclo[2.2.2]octane-3,2'-oxirane] hydrochloride; 3-Oxiranyl-1-azabicyclo[2.2.2]octane hydrochloride; 1-Azabicyclo[2.2.2]octane-3-spiro-2'-oxirane hydrochloride; Spiro(1-azabicyclo[2.2.2]octane-3,2'-oxirane) HCl; Quinuclidine-3-spiro-2'-oxirane hydrochloride; (1R,3R,5S)-8-Oxabicyclo[3.2.1]oct-6-en-3-ol hydrochloride (related stereoisomer); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our Spiro[1-Azabicyclo[2.2.2]Octane-3,2'-Oxirane] Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data to support its use in regulated research environments. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.