Description

Spiro[Cyclopropane-1,2'-[2H]Indol]-3'(1'H)-One CAS NO 64053-78-7 is a specialized spirocyclic organic compound featuring a fused cyclopropane-indolone structure. This unique molecular architecture makes it a valuable and versatile advanced pharmaceutical intermediate (API) and a key building block in synthetic organic chemistry. It is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Utilized in constructing complex spirocyclic and heterocyclic frameworks due to its reactive functional groups and constrained geometry.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening in drug discovery programs.
• Agrochemical Research: Investigated as a potential intermediate for developing new crop protection agents with novel modes of action.
• Material Science Precursor: Explored for the synthesis of organic electronic materials and specialty polymers requiring rigid, three-dimensional components.

Basic Information

Item	Details
Product Name	Spiro[Cyclopropane-1,2'-[2H]Indol]-3'(1'H)-One
CAS No.	64053-78-7
Molecular Formula	C10H7NO
Molecular Weight	157.17 g/mol
Synonyms	1'H-Spiro[cyclopropane-1,2'-indole]-3'-one; 1'H-Spiro(cyclopropane-1,2'-indol)-3'-one; Spiro(cyclopropane-1,2'-indol)-3'-one; 3'H-Spiro[cyclopropane-1,2'-indole]-3'-one; Spiro[cyclopropane-1,2'-indol]-3'(1'H)-one; 64053-78-7; Spiro(cyclopropane-1,2-indol)-3-one
EINECS	Contact for details

Quality Control

Our Spiro[Cyclopropane-1,2'-[2H]Indol]-3'(1'H)-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.