Description

2-(Hydroxymethyl)-2-(p-Tolyloxymethyl)-1,3-Propanediol is a versatile polyol derivative with a unique molecular structure featuring both hydroxymethyl and aryloxymethyl functionalities. This compound serves as a valuable specialty intermediate and building block in advanced organic synthesis, enabling the creation of complex molecules with tailored properties. It is primarily sought after by R&D chemists and process engineers in the pharmaceutical, polymer, and fine chemical industries for developing novel materials, active ingredients, and functional additives.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a rigid, functionalized polyol core.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polyesters, polyurethanes, and epoxy resins, imparting specific solubility or thermal characteristics.
• Liquid Crystal & OLED Materials: Serves as a key precursor for synthesizing advanced organic electronic materials due to its ability to introduce both aromatic and aliphatic hydroxyl groups.
• Dendrimer & Hyperbranched Polymer Synthesis: Utilized as a multifunctional branching unit to construct complex, three-dimensional macromolecular architectures.
• Surface Coatings & Adhesives: Incorporated into formulations to modify flexibility, adhesion, and curing profiles of high-performance coatings.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(Hydroxymethyl)-2-(p-Tolyloxymethyl)-1,3-Propanediol
CAS No.	64049-38-3
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	2,2-Bis(hydroxymethyl)-1,3-propanediol, 4-methylphenyl ether; 2-(p-Tolyloxymethyl)-2-(hydroxymethyl)-1,3-propanediol; 1,1,1-Tris(hydroxymethyl)ethane p-tolyl ether; p-Tolyl 2,2-bis(hydroxymethyl)propyl ether; Tris(hydroxymethyl)ethane p-tolyl ether; 2-(Hydroxymethyl)-2-[(4-methylphenoxy)methyl]-1,3-propanediol; 2,2-Bis(hydroxymethyl)propyl 4-methylphenyl ether
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)-2-(p-Tolyloxymethyl)-1,3-Propanediol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other relevant global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.