Description

N,N'-(2-Hydroxytrimethylene)Bis(Chloroacetamide) is a specialized bifunctional organic compound featuring chloroacetamide groups linked by a hydroxytrimethylene spacer. This molecular architecture makes it a valuable versatile chemical intermediate for synthesizing more complex structures, particularly in advanced material science and pharmaceutical research. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring bifunctional linking or specific amide functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its reactive chloro and amide groups are utilized.
• Polymer Cross-linking Agent: Serves as a cross-linker or chain extender in the manufacture of specialty polymers, resins, and coatings to enhance thermal and mechanical properties.
• Bioconjugation Reagent: Employed in biochemical research for modifying proteins, peptides, or other biomolecules due to its reactive chloroacetamide groups.
• Organic Synthesis Reagent: A versatile reagent in academic and industrial organic chemistry labs for constructing complex heterocycles and other molecular frameworks.
• Material Science Research: Used in the development of advanced functional materials, including dendrimers, gels, and metal-organic frameworks (MOFs).

Basic Information

Product Name	N,N'-(2-Hydroxytrimethylene)Bis(Chloroacetamide)
CAS No.	64049-31-6
Molecular Formula	C7H12Cl2N2O3
Molecular Weight	243.09 g/mol
Synonyms	1,3-Bis(chloroacetamido)-2-propanol; 2-Hydroxy-1,3-bis(chloroacetamido)propane; N,N'-(2-Hydroxy-1,3-propanediyl)bis(2-chloroacetamide); Bis(chloroacetamido)hydroxypropane; Chloroacetamide, N,N'-(2-hydroxytrimethylene)di-; 1,3-Propanediol, 2-hydroxy-, bis(chloroacetate) (related ester); Glycerol 1,3-bis(chloroacetamide)
EINECS	Contact for details

Quality Control

Our N,N'-(2-Hydroxytrimethylene)Bis(Chloroacetamide) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, IR for identification, and residual solvent analysis to ensure it meets precise customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.