Description

9-Amino-2-Acridinecarboxylic Acid Methyl Ester is a high-purity, functionalized acridine derivative of significant interest in advanced organic synthesis and life sciences research. This compound serves as a versatile and critical building block for the development of novel fluorescent probes, DNA intercalators, and pharmaceutical intermediates. It is essential for researchers and manufacturers in the fields of medicinal chemistry, analytical chemistry, and materials science who require a reliable source of this specialized heterocyclic scaffold.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel acridine-based therapeutic agents, including potential anticancer and antimicrobial compounds.
• Fluorescent Probe Synthesis: Used to create sensitive and selective fluorescent dyes and labels for bioimaging, cellular staining, and diagnostic assays.
• DNA/RNA Intercalator Research: Serves as a core structure for developing compounds that bind to nucleic acids, useful in molecular biology and genetics studies.
• Organic Electronic Materials: Acts as a building block for constructing advanced organic semiconductors and light-emitting materials due to the acridine core's photophysical properties.
• Chemical Biology Tool: Employed in the design of activity-based probes and enzyme inhibitors for mechanistic studies and target identification.
• Analytical Chemistry Standard: Utilized as a reference standard or reagent in chromatographic and spectroscopic method development.

Basic Information

Product Name	9-Amino-2-Acridinecarboxylic Acid Methyl Ester
CAS No.	64046-78-2
Molecular Formula	C16H14N2O2
Molecular Weight	266.30 g/mol
Synonyms	Methyl 9-Amino-2-acridinecarboxylate; 2-(Methoxycarbonyl)-9-acridinamine; 9-Aminoacridine-2-carboxylic Acid Methyl Ester; 9-Amino-2-carbomethoxyacridine; Acridine-2-carboxylic acid, 9-amino-, methyl ester; 9-Amino-2-(methoxycarbonyl)acridine
EINECS	Contact for details

Quality Control

Our 9-Amino-2-Acridinecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.