Description

Ethylmethylthiambutene Hydrochloride is a synthetic opioid analgesic compound of significant interest in pharmaceutical research and development. This substance is valued for its specific pharmacological profile, making it a critical intermediate in the study of analgesic pathways and receptor interactions. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and chemical manufacturers focused on developing or analyzing controlled therapeutic substances.

Application

• Pharmaceutical Research Intermediate: Serves as a key chemical building block in the synthesis and study of novel analgesic compounds.
• Analytical Reference Standard: Used as a high-purity standard in chromatographic analysis (HPLC, GC-MS) for quality control and forensic testing.
• Biochemical Research: Employed in in-vitro studies to investigate opioid receptor binding affinity, selectivity, and signal transduction mechanisms.
• Metabolism and Toxicology Studies: Utilized in research to understand the metabolic pathways, pharmacokinetics, and toxicological profile of thiambutene derivatives.
• Chemical Synthesis: Acts as a precursor for the preparation of other specialized thiambutene analogs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Ethylmethylthiambutene Hydrochloride
CAS No.	64037-50-9
Molecular Formula	C15H23NOS • HCl
Molecular Weight	293.87 g/mol (Free base: 257.41 g/mol)
Synonyms	N-Ethyl-N-[2-(methylamino)propyl]-2,2-diphenylthioacetamide Hydrochloride; 1-Ethyl-2-methyl-3-(2,2-diphenylthioacetamido)propylamine Hydrochloride; EMT Hydrochloride; Ethylmethylthiambutene HCl; NIH 5145; Thiambutene derivative; N,N-Diethyl-2,2-diphenyl-4-methylaminothioacetamide Hydrochloride
EINECS	Contact for details

Quality Control

Our Ethylmethylthiambutene Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances and residual solvents, to ensure it meets exacting standards for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.