Description

10,11-Dihydrospiro[5H-Dibenzo[A,D]Cycloheptene-5,3'-Pyrrolidin]-5'-One is a high-purity organic compound featuring a complex spirocyclic and tricyclic fused ring structure. This compound serves as a critical advanced intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and novel chemical entities. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Organic Synthesis Research: Used in academic and industrial research for constructing complex polycyclic molecular frameworks.
• Chemical Reference Standard: Serves as a high-purity standard for analytical method development and quality control in API manufacturing.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing reaction conditions for commercial production.

Basic Information

Product Name	10,11-Dihydrospiro[5H-Dibenzo[A,D]Cycloheptene-5,3'-Pyrrolidin]-5'-One
CAS No.	64036-49-3
Molecular Formula	C19H19NO
Molecular Weight	277.36 g/mol
Synonyms	10,11-Dihydrospiro[dibenzo[a,d]cycloheptene-5,3'-pyrrolidin]-5'-one; Spiro[dibenzo[a,d]cycloheptene-5,3'-pyrrolidine]-5'-one, 10,11-dihydro-; 5'H-Spiro[dibenzo[a,d]cycloheptene-5,3'-pyrrolidin]-5'-one, 10,11-dihydro-; 64036-49-3; Dihydrospirodibenzocycloheptenepyrrolidinone
EINECS	Contact for details

Quality Control

Our production of 10,11-Dihydrospiro[5H-Dibenzo[A,D]Cycloheptene-5,3'-Pyrrolidin]-5'-One adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.