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α-Neu5Ac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-Glc Sodium Salt CAS NO 64003-55-0
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CAS No.:64003-55-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
α-Neu5Ac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-Glc Sodium Salt is a complex, defined oligosaccharide derivative, specifically a sialylated tetrasaccharide, that serves as a critical biochemical tool and reference standard. Its precise structure makes it invaluable for studying carbohydrate-protein interactions, particularly those involving sialic acid and lectins. This high-purity compound is essential for researchers and developers in glycobiology, pharmaceutical R&D, and diagnostic assay development, where it is used to probe biological recognition events, develop inhibitors, and calibrate analytical systems.
Application
- Glycobiology Research: As a key substrate and reference standard for studying sialyltransferase and neuraminidase (sialidase) enzyme activity and specificity.
- Pharmaceutical Development: Used in the discovery and screening of novel therapeutics targeting influenza, bacterial infections, and cancer, where sialic acid-mediated recognition is a critical pathway.
- Diagnostic Reagent Manufacturing: Serves as a critical component or calibrator in immunoassays and lectin-based diagnostic kits for detecting pathogens or disease biomarkers.
- Biochemical Tool: Employed in surface plasmon resonance (SPR), microarray, and other biophysical techniques to characterize binding kinetics and affinity of lectins, antibodies, and viral hemagglutinins.
- Enzyme Inhibition Studies: Acts as a substrate analog for developing and testing inhibitors of glycosyltransferases and glycosidases.
- Cell Biology & Immunology: Used to modulate cell surface interactions and study the role of sialylated glycans in cell signaling, adhesion, and immune response.
Basic Information
| Product Name | α-Neu5Ac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-Glc Sodium Salt |
| CAS No. | 64003-55-0 |
| Molecular Formula | C38H61N3O30Na |
| Molecular Weight | 1038.87 g/mol (anhydrous basis) |
| Synonyms | Neu5Acα2-6Galβ1-4GlcNAcβ1-3Galβ1-4Glc Sodium Salt; Sialyl Lacto-N-neotetraose c Sodium Salt; LST c Sodium Salt; 6'-Sialyllacto-N-neotetraose Sodium Salt; α-N-Acetylneuraminyl-(2→6)-β-D-galactopyranosyl-(1→4)-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→3)-β-D-galactopyranosyl-(1→4)-D-glucopyranose Sodium Salt; Sialylated LNnT Sodium Salt |
| EINECS | Contact for details |
Quality Control
Every batch of our α-Neu5Ac-[2->6]-β-Gal-[1->4]-β-Glcnac-[1->3]-β-Gal-[1->4]-Glc Sodium Salt is produced and analyzed under strict quality management protocols. We guarantee high purity and structural integrity, verified by advanced analytical techniques including NMR and mass spectrometry. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95% |
| Water Content (KF) | ≤ 5.0 % |
| Specific Rotation | Contact for details |
| Bacterial Endotoxins | < 1.0 EU/mg (if applicable) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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