Description

1-Hydroxy-2-Indanacetic Acid is a versatile indane derivative that serves as a key chiral building block and intermediate in advanced organic synthesis. Its unique structure, featuring both a carboxylic acid and a phenolic hydroxyl group, makes it valuable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory conditions.
• Chiral Synthesis: Utilized as a starting material or resolving agent for the production of enantiomerically pure compounds due to its inherent stereogenic center.
• Ligand and Catalyst Development: Serves as a scaffold for creating novel ligands used in asymmetric catalysis and metal complexation.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring the indane core structure.
• Academic and R&D: Used in university and corporate research laboratories for method development and exploring new chemical reactions.

Basic Information

Product Name	1-Hydroxy-2-Indanacetic Acid
CAS No.	63992-22-3
Molecular Formula	C11H12O3
Molecular Weight	192.21 g/mol
Synonyms	2-(1-Hydroxy-2-indanyl)acetic Acid; (1-Hydroxy-2-indanyl)acetic Acid; 1-Hydroxyindane-2-acetic Acid; α-(1-Hydroxy-2-indanyl)acetic Acid; 2-Indanol-1-acetic Acid, 1-Hydroxy-; 1-Hydroxy-2-indaneacetic Acid; 2-(1-Hydroxyindan-2-yl)acetic Acid
EINECS	Contact for details

Quality Control

Our 1-Hydroxy-2-Indanacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom purity grades are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.