Description

(1R,3Aα,5Aβ,6β,9Aβ)-Dodecahydro-6-[(Z)-2,4-Pentadienyl]Pyrrolo[1,2-A]Quinoline-1β-Ethanol is a complex, stereochemically defined alkaloid derivative with significant synthetic utility. This compound matters as a versatile chiral building block and key intermediate in the synthesis of complex natural products and pharmacologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in advanced organic synthesis, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Advanced Pharmaceutical Intermediates: Serves as a critical chiral scaffold for the synthesis of potential drug candidates targeting neurological and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its complex polycyclic framework.
• Natural Product Synthesis: Acts as a key intermediate in the total synthesis of complex indole and quinoline-based alkaloids.
• Asymmetric Catalysis Studies: Employed as a substrate or ligand precursor in the development of new stereoselective synthetic methodologies.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying biological pathways and protein interactions.
• High-Purity Reference Standards: Supplied as a certified reference material for analytical method development and quality control in pharmaceutical R&D.

Basic Information

Product Name	(1R,3Aα,5Aβ,6β,9Aβ)-Dodecahydro-6-[(Z)-2,4-Pentadienyl]Pyrrolo[1,2-A]Quinoline-1β-Ethanol
CAS No.	63983-58-4
Molecular Formula	C19H29NO
Molecular Weight	287.44 g/mol
Synonyms	6-[(2Z,4E)-2,4-Pentadien-1-yl]dodecahydro-1H-pyrrolo[1,2-a]quinolin-1-ol; (1R,3aα,5aβ,6β,9aβ)-Dodecahydro-6-[(2Z,4E)-2,4-pentadien-1-yl]pyrrolo[1,2-a]quinoline-1β-ethanol; 1H-Pyrrolo[1,2-a]quinoline-1-ethanol, dodecahydro-6-[(2Z,4E)-2,4-pentadienyl]-, (1R,3aα,5aβ,6β,9aβ)-; Dodecahydro-6-[(2Z,4E)-2,4-pentadienyl]pyrrolo[1,2-a]quinoline-1β-ethanol; A key intermediate for the synthesis of complex alkaloids.
EINECS	Contact for details

Quality Control

Our high-value chemical intermediates are produced under strict quality management systems. Each batch of (1R,3Aα,5Aβ,6β,9Aβ)-Dodecahydro-6-[(Z)-2,4-Pentadienyl]Pyrrolo[1,2-A]Quinoline-1β-Ethanol undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and chiral analysis to verify stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C under an inert atmosphere. The compound is moisture-sensitive; ensure the container is kept in a cool, dry place. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.