Description

4'-[2-Hydroxy-3-(4-Phenylpiperazino)Propoxy]Chalcone is a synthetic chalcone derivative characterized by its unique molecular structure incorporating a phenylpiperazine moiety. This compound is of significant interest in pharmaceutical research and development due to its potential as a key intermediate or active scaffold for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for investigating new drug candidates targeting central nervous system and inflammatory pathways.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biochemical Tool Compound: Employed in vitro and in vivo to study specific biological pathways and receptor interactions related to its pharmacological profile.
• Reference Standard: Provides a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Preclinical Development: Supports early-stage drug discovery programs focusing on anti-inflammatory, neuroprotective, or anticancer agents.

Basic Information

Product Name	4'-[2-Hydroxy-3-(4-Phenylpiperazino)Propoxy]Chalcone
CAS No.	63937-18-8
Molecular Formula	C28H30N2O3
Molecular Weight	442.55 g/mol
Synonyms	4'-[2-Hydroxy-3-(4-Phenyl-1-piperazinyl)propoxy]chalcone; 1-[4-[3-(4-Phenyl-1-piperazinyl)-2-hydroxypropoxy]phenyl]-3-phenyl-2-propen-1-one; 2-Propen-1-one, 1-[4-[3-(4-phenyl-1-piperazinyl)-2-hydroxypropoxy]phenyl]-3-phenyl-; Chalcone derivative 63937-18-8; (E)-1-(4-(3-(4-phenylpiperazin-1-yl)-2-hydroxypropoxy)phenyl)-3-phenylprop-2-en-1-one
EINECS	Contact for details

Quality Control

Our 4'-[2-Hydroxy-3-(4-Phenylpiperazino)Propoxy]Chalcone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.