Description

(R)-2-Hydroxy-2-Methylbenzenepropanoic Acid is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry makes it a valuable precursor for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications requiring precise molecular architecture.

Application

• Key chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Building block for advanced agrochemicals, including herbicides and plant growth regulators, where stereochemistry influences biological activity.
• Precursor in asymmetric synthesis and catalysis research for developing novel synthetic methodologies.
• Intermediate for manufacturing specialty polymers and liquid crystals with specific optical properties.
• Starting material for producing fine chemicals and flavors & fragrances requiring high enantiomeric purity.
• Reference standard in analytical chemistry for method development and quality control in chiral separations.

Basic Information

Product Name	(R)-2-Hydroxy-2-Methylbenzenepropanoic Acid
CAS No.	63742-14-3
Molecular Formula	C10H12O3
Molecular Weight	180.20 g/mol
Synonyms	(R)-2-(2-Hydroxy-2-methylpropyl)benzoic Acid; (R)-α-Hydroxy-α-methyl-3-phenylpropionic Acid; (R)-2-Hydroxy-2-methyl-3-phenylpropanoic Acid; (R)-HMPPA; Benzenepropanoic acid, 2-hydroxy-2-methyl-, (αR)-; (R)-2-Methyl-2-hydroxy-3-phenylpropionic Acid
EINECS	Contact for details

Quality Control

Our (R)-2-Hydroxy-2-Methylbenzenepropanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.