Description

1-Chloro-4-Fluoro-1-Nitrobutane is a specialized halogenated nitroalkane building block of significant interest in advanced organic synthesis. This compound matters for its unique bifunctional reactivity, offering distinct handles for nucleophilic substitution and nitro group transformations. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine atom can improve pesticidal activity and environmental profile.
• Fluorinated Building Block: A versatile reagent for introducing both fluorine and nitro functional groups into target molecules, enabling further derivatization to amines, carbonyls, and other valuable groups.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialty polymers with unique surface properties or reactivity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems, leveraging the distinct properties of the fluorine atom.

Basic Information

Product Name	1-Chloro-4-Fluoro-1-Nitrobutane
CAS No.	63732-17-2
Molecular Formula	C₄H₇ClFNO₂
Molecular Weight	155.56 g/mol
Synonyms	4-Fluoro-1-chloro-1-nitrobutane; 1-Nitro-1-chloro-4-fluorobutane; Butane, 1-chloro-4-fluoro-1-nitro-; γ-Fluoro-γ-chloro-γ-nitrobutane; 1-Chloro-4-fluoro-1-nitro-butane; FCB Nitrochloride (contextual); Nitrochlorofluorobutane
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Fluoro-1-Nitrobutane is produced under stringent quality management protocols. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in darkness.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Density (20°C)	~1.30 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.