Description

1-Oxo-4,4A,5,6-Tetrahydro-1H-Pyrimido[1,2-A]Quinoline-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex fused-ring heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new therapeutic agents and specialty products.

Application

• Pharmaceutical Intermediate: A key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Organic Synthesis Building Block: Used in complex multi-step organic syntheses to construct intricate polycyclic frameworks found in bioactive molecules.
• Agrochemical Research: Serves as a starting material for developing new pesticides or herbicides with specific modes of action.
• Academic & R&D Laboratories: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals requiring this specific heterocyclic scaffold.

Basic Information

Product Name	1-Oxo-4,4A,5,6-Tetrahydro-1H-Pyrimido[1,2-A]Quinoline-2-Carboxylic Acid Ethyl Ester
CAS No.	63658-84-4
Molecular Formula	C₁₅H₁₆N₂O₃
Molecular Weight	272.30 g/mol
Synonyms	Ethyl 1-oxo-4,4a,5,6-tetrahydro-1H-pyrimido[1,2-a]quinoline-2-carboxylate; Pyrimido[1,2-a]quinoline-2-carboxylic acid, 1,4,4a,5,6,7-hexahydro-1-oxo-, ethyl ester; 1H-Pyrimido[1,2-a]quinoline-2-carboxylic acid, 1,4,4a,5,6,7-hexahydro-1-oxo-, ethyl ester; Ethyl 1-oxo-1,4,4a,5,6,7-hexahydropyrimido[1,2-a]quinoline-2-carboxylate; CAS 63658-84-4
EINECS	Contact for details

Quality Control

Our 1-Oxo-4,4A,5,6-Tetrahydro-1H-Pyrimido[1,2-A]Quinoline-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.