Description

(R)-(-)-2-Methoxy-2-(1-Naphthyl)Propionic Acid is a high-purity chiral carboxylic acid derivative, serving as a critical chiral resolving agent and synthetic intermediate. Its primary value lies in its ability to separate enantiomers of amines and other basic compounds, which is essential for producing optically pure pharmaceuticals. This compound is indispensable for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where stereochemical control is paramount for product efficacy and safety.

Application

• Chiral Resolution Agent: Widely used for the enantiomeric separation of racemic amines and amino alcohols in pharmaceutical development.
• Pharmaceutical Intermediate: Serves as a key building block in the asymmetric synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Analytical Chemistry Standard: Employed as a reference standard in HPLC and chiral chromatography methods for method development and validation.
• Catalyst and Ligand Synthesis: Used in the preparation of chiral catalysts and ligands for asymmetric synthesis reactions.
• Agrochemical Research: Acts as an intermediate in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Industrial R&D: A valuable tool for research in organic chemistry, medicinal chemistry, and process chemistry focused on stereoselective transformations.

Basic Information

Product Name	(R)-(-)-2-Methoxy-2-(1-Naphthyl)Propionic Acid
CAS No.	63628-26-2
Molecular Formula	C₁₅H₁₆O₃
Molecular Weight	244.29 g/mol
Synonyms	(R)-2-Methoxy-2-(1-naphthyl)propanoic acid; (R)-Methoxy(1-naphthyl)acetic acid methyl ester derivative; (R)-α-Methoxy-α-(1-naphthyl)propionic acid; (R)-MNAP; (R)-(-)-Methoxy(1-naphthyl)acetic acid methyl analog; (R)-2-Methoxy-2-(naphthalen-1-yl)propanoic acid; (R)-1-Naphthylmethoxyacetic acid derivative; (R)-O-Methylmandelic acid 1-naphthyl analog
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Methoxy-2-(1-Naphthyl)Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for chiral synthesis and resolution. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided to guarantee reliable and consistent performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (ee)	≥99.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.