Description

Z-Gly-Nva-OH is a protected dipeptide building block widely used in solid-phase peptide synthesis (SPPS). This compound is essential for researchers and manufacturers requiring high-purity intermediates to construct complex peptide sequences with precise control. It is particularly valuable for the pharmaceutical and biotechnology industries in the development of therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Pharmaceutical Intermediates: A key raw material in the synthesis of active pharmaceutical ingredients (APIs) for peptide-based drugs.
• Biochemical Research: Used as a building block in academic and industrial research for studying protein structure, function, and interactions.
• Peptide Library Synthesis: Enables the combinatorial creation of diverse peptide libraries for drug discovery and screening applications.
• Custom Peptide Production: Serves as a critical component for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides.
• Proteomics & Diagnostics: Employed in the development of peptide standards, probes, and reagents for diagnostic assays and proteomic studies.

Basic Information

Product Name	Z-Gly-Nva-OH
CAS No.	63623-57-4
Molecular Formula	C15H20N2O5
Molecular Weight	308.33 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]glycyl-L-norvaline; Z-Gly-L-Nva-OH; CBZ-Glycyl-L-norvaline; Benzyloxycarbonyl-glycyl-norvaline; Nα-Carbobenzoxy-glycyl-L-norvaline; (S)-2-((((Benzyloxy)carbonyl)glycyl)amino)pentanoic acid; Z-Gly-Norval-OH; N-CBZ-Glycyl-L-norvaline
EINECS	Contact for details

Quality Control

Our Z-Gly-Nva-OH is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation	-15° to -20° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.