Description

cis-Cyclopentane-1,3-Diamine Dihydrochloride is a high-purity, chiral diamine salt with significant utility as a key building block in advanced organic synthesis. Its rigid cis-cyclopentane backbone and dual amine functionality make it a valuable precursor for creating complex molecular architectures, particularly in the development of chiral ligands, catalysts, and active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific stereochemistry and enhanced biological activity.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Chiral Ligand & Catalyst Synthesis: Serves as a core scaffold for developing enantioselective ligands and organocatalysts used in asymmetric synthesis to produce single-enantiomer compounds.
• Agrochemical Research: Used in the creation of new, more effective herbicides, fungicides, and insecticides with targeted activity and improved environmental profiles.
• Polymer & Material Science: Functions as a monomer or cross-linking agent for producing specialty polyamides, polyurethanes, and epoxy resins with unique thermal and mechanical properties.
• Chelating Agent Precursor: The diamine structure is ideal for synthesizing chelating agents used in metal ion sequestration, catalysis, and diagnostic imaging.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and constructing complex, stereodefined molecular frameworks.

Basic Information

Product Name	cis-Cyclopentane-1,3-Diamine Dihydrochloride
CAS No.	63591-57-1
Molecular Formula	C5H14Cl2N2
Molecular Weight	173.08 g/mol
Synonyms	(1R,3S)-1,3-Cyclopentanediamine dihydrochloride; (1S,3R)-1,3-Cyclopentanediamine dihydrochloride; cis-1,3-Diaminocyclopentane dihydrochloride; (1R,3S)-Cyclopentane-1,3-diamine dihydrochloride; (1S,3R)-Cyclopentane-1,3-diamine dihydrochloride; 1,3-Cyclopentanediamine, (1R,3S)-, dihydrochloride; 1,3-Cyclopentanediamine, (1S,3R)-, dihydrochloride; (+/-)-cis-1,3-Diaminocyclopentane dihydrochloride
EINECS	Contact for details

Quality Control

Our cis-Cyclopentane-1,3-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity (HPLC/Chiral HPLC), residual solvents, and related substances is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.