Description

(2R,3'S)-5'α-[(E)-5-(3-Furyl)-2-Methyl-1-Pentenyl]-1',2',3',3'Aα,5',7'Aβ-Hexahydro-3-Hydroxy-3'α,4,7'-Trimethylspiro[Furan-2(5H),4'-[4H]Inden]-5-One is a complex, high-purity spirocyclic organic compound characterized by its unique stereochemistry and functional groups. This compound serves as a critical advanced pharmaceutical intermediate (API) or a key building block in sophisticated organic synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in areas requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery and development.
• Organic Synthesis Building Block: Used in complex multi-step syntheses, including asymmetric synthesis, to construct intricate molecular frameworks.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the creation of targeted compound libraries for biological screening.
• Chemical Reference Standard: Serves as a high-purity analytical standard for method development, validation, and quality control in analytical laboratories.
• Academic & Industrial R&D: Utilized in research exploring new synthetic methodologies, catalysis, and the properties of complex heterocyclic systems.

Basic Information

Product Name	(2R,3'S)-5'α-[(E)-5-(3-Furyl)-2-Methyl-1-Pentenyl]-1',2',3',3'Aα,5',7'Aβ-Hexahydro-3-Hydroxy-3'α,4,7'-Trimethylspiro[Furan-2(5H),4'-[4H]Inden]-5-One
CAS No.	63555-48-6
Molecular Formula	C28H34O4
Molecular Weight	434.57 g/mol
Synonyms	Spiro[Furan-2(5H),4'-[4H]Inden]-5-One, (2R,3'S)-5'α-[(E)-5-(3-Furyl)-2-Methyl-1-Pentenyl]-1',2',3',3'Aα,5',7'Aβ-Hexahydro-3-Hydroxy-3'α,4,7'-Trimethyl-; (2R,3'S)-5'α-[(E)-5-(3-Furyl)-2-Methylpent-1-enyl]-1',2',3',3'aα,5',7'aβ-Hexahydro-3-Hydroxy-3'α,4,7'-Trimethylspiro[furan-2(5H),4'-[4H]Inden]-5-One; Spirofuran Indenone Derivative; Complex Spirocyclic Furanone; CAS 63555-48-6
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP-grade production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.