Description

D-β-Homoglutamic Acid-Hcl CAS NO 63492-85-3 is a high-purity, non-proteinogenic amino acid derivative, specifically the D-isomer of β-homoglutamic acid in its hydrochloride salt form. This compound is a critical chiral building block and intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Biochemical Research: Used as a substrate or analog in enzymatic studies, metabolic pathway investigations, and receptor-ligand binding assays.
• Peptide Synthesis: Serves as a protected or modified amino acid residue in solid-phase and solution-phase peptide chemistry to alter peptide properties.
• Neurology Research: Investigated for its potential role and effects as a glutamate analog in neurological studies.
• Standards & Reference Materials: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Fine Chemical Synthesis: A versatile intermediate for creating complex organic molecules with specific stereochemical requirements.

Basic Information

Item	Details
Product Name	D-β-Homoglutamic Acid Hydrochloride
CAS No.	63492-85-3
Molecular Formula	C6H11NO4 • HCl
Molecular Weight	197.62 g/mol
Synonyms	(R)-2-Aminopimelic acid hydrochloride; D-2-Aminoheptanedioic acid hydrochloride; D-β-Homoglutamic acid HCl; (2R)-2-Aminopimelic acid hydrochloride; D-α-Aminopimelic acid hydrochloride; (R)-2-Aminoheptanedioic acid hydrochloride; D-APMA hydrochloride
EINECS	Contact for details

Quality Control

Our D-β-Homoglutamic Acid-Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and specific impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.