Description

(S)-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Methyl Ester is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and functionalized tetrahydroquinoline scaffold, which is a privileged structure in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of biologically active molecules, particularly in the development of central nervous system (CNS) agents and enzyme inhibitors.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides that leverage the tetrahydroquinoline pharmacophore.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective transformations.
• Chemical Biology & Proteomics: Employed as a scaffold for designing molecular probes and activity-based protein profiling (ABPP) reagents.
• Academic & R&D Laboratories: A valuable compound for methodological studies in synthetic organic chemistry and medicinal chemistry programs.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products and other high-value specialty chemicals.

Basic Information

Product Name	(S)-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Methyl Ester
CAS No.	63492-82-0
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(S)-1,2,3,4-Tetrahydro-2-quinolinecarboxylic acid methyl ester; Methyl (S)-1,2,3,4-tetrahydroquinoline-2-carboxylate; (S)-Methyl 1,2,3,4-tetrahydro-2-quinolinecarboxylate; (S)-Tetrahydroquinoline-2-carboxylic acid methyl ester; L-Tetrahydroquinoline-2-carboxylic acid methyl ester; (2S)-1,2,3,4-Tetrahydroquinoline-2-carboxylic Acid Methyl Ester; (S)-2-Methoxycarbonyl-1,2,3,4-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our (S)-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure high chemical and chiral purity, meeting the exacting standards of research and production. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.