Description

cis-Cyclopropane-1,2-Diamine Dihydrochloride is a high-purity, chiral diamine salt of significant synthetic utility. This compound serves as a crucial building block and chiral ligand in asymmetric synthesis, enabling the creation of complex molecules with high stereoselectivity. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for antiviral, antibacterial, and central nervous system (CNS) active compounds.
• Asymmetric Catalyst Ligand: Used to construct chiral ligands for transition metal catalysts in enantioselective hydrogenation, cyclopropanation, and other C-C bond-forming reactions.
• Agrochemical Synthesis: Employed in the development of chiral pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Peptidomimetics & Bioactive Molecule Design: The rigid cyclopropane backbone and diamine functionality make it valuable for constructing conformationally restricted peptide analogs and other bioactive scaffolds.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for producing specialty polymers with unique thermal and mechanical properties.
• Chelating Agent: Forms stable complexes with metal ions, useful in analytical chemistry and metal sequestration applications.

Basic Information

Product Name	cis-Cyclopropane-1,2-Diamine Dihydrochloride
CAS No.	63466-89-7
Molecular Formula	C3H10N2·2HCl
Molecular Weight	159.05 g/mol
Synonyms	(1R,2S)-1,2-Diaminocyclopropane Dihydrochloride; (1S,2R)-1,2-Diaminocyclopropane Dihydrochloride; cis-1,2-Diaminocyclopropane Dihydrochloride; (1R,2S)-Cyclopropane-1,2-diamine Dihydrochloride; (1S,2R)-Cyclopropane-1,2-diamine Dihydrochloride; (1R,2S)-1,2-Cyclopropanediamine Dihydrochloride; (1S,2R)-1,2-Cyclopropanediamine Dihydrochloride; (+)-cis-1,2-Diaminocyclopropane Dihydrochloride
EINECS	Contact for details

Quality Control

Our cis-Cyclopropane-1,2-Diamine Dihydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We ensure compliance with relevant global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.