Description

5-[4-Acetamidophenoxy]-8-Amino-6-Methoxyquinoline CAS NO 63460-39-9 is a specialized quinoline derivative with a unique acetamidophenoxy substitution pattern. This compound is valued as a key synthetic intermediate and a potential pharmacophore in advanced research and development. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and academic researchers focused on medicinal chemistry and heterocyclic compound synthesis.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, or anti-cancer agents.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to develop new bioactive molecules with optimized properties.
• Agrochemical Development: Acts as a precursor in the creation of new pesticides or herbicides, leveraging the biological activity of the quinoline moiety.
• Chemical Biology Probes: Utilized in the development of fluorescent probes or enzyme inhibitors for biochemical pathway analysis.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental research in organic synthesis and heterocyclic chemistry.
• Material Science Precursor: Investigated as a starting material for synthesizing organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Product Name	5-[4-Acetamidophenoxy]-8-Amino-6-Methoxyquinoline
CAS No.	63460-39-9
Molecular Formula	C18H17N3O3
Molecular Weight	323.35 g/mol
Synonyms	8-Amino-5-(4-acetamidophenoxy)-6-methoxyquinoline; 5-(4-Acetamidophenoxy)-8-amino-6-methoxyquinoline; 6-Methoxy-5-(4-acetamidophenoxy)quinolin-8-amine; 5-(p-Acetamidophenoxy)-8-amino-6-methoxyquinoline; 8-Amino-6-methoxy-5-(4-acetamidophenoxy)quinoline; Quinoline, 8-amino-5-[4-(acetylamino)phenoxy]-6-methoxy-
EINECS	Contact for details

Quality Control

Our 5-[4-Acetamidophenoxy]-8-Amino-6-Methoxyquinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR). A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to ensure traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.