Description

2,2'-Biquinoline-4,4'-Dicarboxylic Acid Dipotassium Salt Trihydrate is a high-purity, water-soluble complexometric reagent and analytical standard. This compound is valued for its exceptional chelating properties, particularly with copper ions, making it a critical component in sensitive colorimetric assays and quantitative analysis. It is primarily sought by research institutions, analytical laboratories, and manufacturers in the pharmaceutical and chemical industries for applications requiring precise metal ion detection and quantification.

Application

• Colorimetric Reagent for Copper Detection (Cuproine Method): The primary application is as a highly selective and sensitive chromogenic agent for the spectrophotometric determination of copper (Cu(I)) in various matrices.
• Analytical Chemistry Standard: Used as a certified reference material (CRM) or high-purity standard for calibrating instruments and validating analytical methods in trace metal analysis.
• Biochemical Research: Employed in studies of metalloproteins and enzymes where copper plays a catalytic role, aiding in the measurement of copper content and binding studies.
• Water and Environmental Analysis: Applied in testing protocols to detect and quantify trace levels of copper in drinking water, wastewater, and environmental samples.
• Pharmaceutical Quality Control: Utilized in assay development and impurity profiling for drug substances and products where copper catalysts or impurities must be monitored.
• Industrial Process Monitoring: Serves as a key reagent in on-line or off-line analytical systems for monitoring copper levels in electroplating baths, alloy production, and catalyst streams.

Basic Information

Product Name	2,2'-Biquinoline-4,4'-Dicarboxylic Acid Dipotassium Salt Trihydrate
CAS No.	63451-34-3
Molecular Formula	C20H10K2N2O4 · 3H2O
Molecular Weight	492.62 g/mol (Trihydrate)
Synonyms	Cuproine Dipotassium Salt; 2,2'-Biquinoline-4,4'-dicarboxylic acid potassium salt trihydrate; 4,4'-Dicarboxy-2,2'-biquinoline dipotassium salt trihydrate; Bicinchoninic Acid Dipotassium Salt Trihydrate; BCA Dipotassium Salt; Bicinchoninate Dipotassium Salt; Cuprizone Analog; (2,2'-Biquinoline)-4,4'-dicarboxylic acid dipotassium salt trihydrate
EINECS	Contact for details

Quality Control

Our 2,2'-Biquinoline-4,4'-Dicarboxylic Acid Dipotassium Salt Trihydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling, to ensure it meets the stringent requirements for analytical reagents and reference standards. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay (by HPLC), loss on drying, heavy metals, and specific absorbance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Once opened, containers should be flushed with an inert gas (e.g., nitrogen or argon) and resealed immediately to prevent moisture uptake and potential degradation.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0% (anhydrous basis)
Loss on Drying	9.0 - 12.0% (Theoretical for Trihydrate: ~10.97%)
Water (Karl Fischer)	9.0 - 12.0%
Absorbance (Specific)	Conforms (at specified wavelength for Cu(I) complex)
Heavy Metals (as Pb)	≤ 20 ppm
Copper (Cu)	≤ 10 ppm
Solubility (in Water)	Clear, yellow solution at 1% w/v

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.