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10,11-Dihydrodiol-8,9-Epoxide Benzanthracene CAS NO 63438-27-7
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CAS No.:63438-27-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
10,11-Dihydrodiol-8,9-Epoxide Benzanthracene is a high-purity, specialized polycyclic aromatic hydrocarbon (PAH) derivative of significant research interest. This compound serves as a critical intermediate and reference standard in the study of metabolic activation pathways and mutagenic mechanisms of benzanthracene derivatives. It is primarily utilized by research institutions and industrial R&D laboratories focused on toxicology, environmental science, and pharmaceutical development.
Application
- Biochemical Research: Used as a key metabolite standard in studies investigating the metabolic activation pathways of benzanthracene and related polycyclic aromatic hydrocarbons.
- Toxicology & Mutagenicity Studies: Serves as a reference compound for in vitro and in vivo assays to understand DNA adduct formation and carcinogenic potential.
- Environmental Analysis: Employed as an analytical standard for the detection and quantification of PAH metabolites in environmental and biological samples.
- Pharmaceutical R&D: Utilized in mechanistic studies related to chemoprevention and the development of compounds that may inhibit metabolic activation of procarcinogens.
- Academic Research: A vital tool for universities and research institutes conducting fundamental studies in organic chemistry, biochemistry, and molecular toxicology.
- Quality Control & Method Development: Acts as a certified reference material (CRM) for calibrating analytical instrumentation like HPLC, GC-MS, and LC-MS in analytical laboratories.
Basic Information
| Product Name | 10,11-Dihydrodiol-8,9-Epoxide Benzanthracene |
| CAS No. | 63438-27-7 |
| Molecular Formula | C20H14O3 |
| Molecular Weight | 302.32 g/mol |
| Synonyms | Benz[a]anthracene 8,9-epoxide-10,11-diol; 10,11-Dihydroxy-8,9-epoxy-8,9,10,11-tetrahydrobenz[a]anthracene; anti-Benz[a]anthracene-8,9-dihydrodiol-10,11-epoxide; BA-8,9-diol-10,11-epoxide; Benzanthracene diol epoxide; 8,9-Dihydroxy-10,11-epoxy-8,9,10,11-tetrahydrobenz[a]anthracene |
| EINECS | Contact for details |
Quality Control
Our 10,11-Dihydrodiol-8,9-Epoxide Benzanthracene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to rigorous internal standards aligned with research-grade chemical requirements, ensuring reliable performance as a reference material.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference |
| Purity (HPLC) | ≥ 95.0% |
| Related Substances (HPLC) | Total impurities ≤ 5.0% |
| Solubility | Soluble in DMSO, Acetone; sparingly soluble in water |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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