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10,11-Dihydrodiol-8,9-Epoxide Benzanthracene CAS NO 63438-27-7


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CAS No.:63438-27-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

10,11-Dihydrodiol-8,9-Epoxide Benzanthracene is a high-purity, specialized polycyclic aromatic hydrocarbon (PAH) derivative of significant research interest. This compound serves as a critical intermediate and reference standard in the study of metabolic activation pathways and mutagenic mechanisms of benzanthracene derivatives. It is primarily utilized by research institutions and industrial R&D laboratories focused on toxicology, environmental science, and pharmaceutical development.

Application

  • Biochemical Research: Used as a key metabolite standard in studies investigating the metabolic activation pathways of benzanthracene and related polycyclic aromatic hydrocarbons.
  • Toxicology & Mutagenicity Studies: Serves as a reference compound for in vitro and in vivo assays to understand DNA adduct formation and carcinogenic potential.
  • Environmental Analysis: Employed as an analytical standard for the detection and quantification of PAH metabolites in environmental and biological samples.
  • Pharmaceutical R&D: Utilized in mechanistic studies related to chemoprevention and the development of compounds that may inhibit metabolic activation of procarcinogens.
  • Academic Research: A vital tool for universities and research institutes conducting fundamental studies in organic chemistry, biochemistry, and molecular toxicology.
  • Quality Control & Method Development: Acts as a certified reference material (CRM) for calibrating analytical instrumentation like HPLC, GC-MS, and LC-MS in analytical laboratories.

Basic Information

Product Name 10,11-Dihydrodiol-8,9-Epoxide Benzanthracene
CAS No. 63438-27-7
Molecular Formula C20H14O3
Molecular Weight 302.32 g/mol
Synonyms Benz[a]anthracene 8,9-epoxide-10,11-diol; 10,11-Dihydroxy-8,9-epoxy-8,9,10,11-tetrahydrobenz[a]anthracene; anti-Benz[a]anthracene-8,9-dihydrodiol-10,11-epoxide; BA-8,9-diol-10,11-epoxide; Benzanthracene diol epoxide; 8,9-Dihydroxy-10,11-epoxy-8,9,10,11-tetrahydrobenz[a]anthracene
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Quality Control

Our 10,11-Dihydrodiol-8,9-Epoxide Benzanthracene is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation, and impurity profiles. We adhere to rigorous internal standards aligned with research-grade chemical requirements, ensuring reliable performance as a reference material.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation and ensure long-term stability. Allow the container to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Solubility Soluble in DMSO, Acetone; sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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