Description

(+)-trans-3,4-Dihydroxy-1,2-Epoxy-1,2,3,4-Tetrahydrobenz(A)Anthracene CAS NO 63438-26-6 is a high-purity, chiral polycyclic aromatic hydrocarbon (PAH) derivative characterized by its specific stereochemistry and functional epoxide and diol groups. This compound is of significant value as a critical advanced synthetic intermediate and a reference standard in research applications requiring precise molecular architecture. It is primarily sought by pharmaceutical R&D and academic research laboratories focused on organic synthesis, chemical biology, and toxicology studies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of complex bioactive molecules and potential drug candidates.
• Biochemical Research: Used as a model compound in studies of polycyclic aromatic hydrocarbon (PAH) metabolism, DNA adduct formation, and mutagenicity mechanisms.
• Reference Standard: Employed as a high-purity analytical standard for method development and calibration in chromatographic (HPLC, GC) and spectroscopic analysis.
• Organic Synthesis: Utilized in stereoselective synthesis and as a precursor for further chemical modifications due to its reactive epoxide and hydroxyl functionalities.
• Toxicology Studies: Acts as a specific metabolite analog in research investigating the carcinogenic pathways of benz(a)anthracene and related PAHs.

Basic Information

Product Name	(+)-trans-3,4-Dihydroxy-1,2-Epoxy-1,2,3,4-Tetrahydrobenz(A)Anthracene
CAS No.	63438-26-6
Molecular Formula	C20H14O3
Molecular Weight	302.32 g/mol
Synonyms	(+)-trans-3,4-Dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz[a]anthracene; (+)-anti-3,4-Dihydroxy-1,2-epoxy-1,2,3,4-tetrahydrobenz[a]anthracene; (+)-anti-BA-3,4-diol-1,2-epoxide; Benz[a]anthracene 3,4-diol 1,2-epoxide, (+)-anti-; 1,2-Epoxy-3,4-dihydroxy-1,2,3,4-tetrahydrobenz[a]anthracene, (+)-trans-; anti-Benzo[a]anthracene-3,4-diol-1,2-epoxide
EINECS	Contact for details

Quality Control

Every batch of our (+)-trans-3,4-Dihydroxy-1,2-Epoxy-1,2,3,4-Tetrahydrobenz(A)Anthracene is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the exacting requirements of research and development. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and other critical parameters are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the container to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.