Description

L-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Hydrochloride is a high-purity, pharmaceutically relevant chiral building block and intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily sought by research institutions, pharmaceutical development labs, and fine chemical manufacturers for producing active pharmaceutical ingredients (APIs) and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Asymmetric Synthesis: Serves as a valuable precursor for constructing complex, enantiomerically pure molecules.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring a tetrahydroquinoline scaffold.
• Biochemical Research: Potential use in developing enzyme inhibitors or receptor ligands due to its structural features.

Basic Information

Product Name	L-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Hydrochloride
CAS No.	63430-98-8
Molecular Formula	C10H12NO2·HCl
Molecular Weight	213.67 g/mol
Synonyms	(2S)-1,2,3,4-Tetrahydroquinoline-2-carboxylic acid hydrochloride; L-Tetrahydroquinoline-2-carboxylic acid HCl; (S)-1,2,3,4-Tetrahydroquinoline-2-carboxylic acid hydrochloride; Quinoline-2-carboxylic acid, 1,2,3,4-tetrahydro-, hydrochloride, L-; (S)-2-Carboxy-1,2,3,4-tetrahydroquinoline hydrochloride; L-THCA HCl
EINECS	Contact for details

Quality Control

Our L-1,2,3,4-Tetrahydro-Quinoline-2-Carboxylic Acid Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.