Description

5-(Chloroacetyl)-8-(Phenylmethoxy)-2(1H)-Quinolinone is a high-purity, advanced pharmaceutical intermediate characterized by its quinolinone core functionalized with chloroacetyl and benzyloxy groups. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and anti-inflammatory drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting kinase inhibition.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in academic and industrial R&D labs.
• Organic Synthesis Building Block: Utilized for constructing complex heterocyclic frameworks due to its reactive chloroacetyl and protected hydroxyl functionalities.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	5-(Chloroacetyl)-8-(Phenylmethoxy)-2(1H)-Quinolinone
CAS No.	63404-86-4
Molecular Formula	C18H14ClNO3
Molecular Weight	327.76 g/mol
Synonyms	8-(Benzyloxy)-5-(chloroacetyl)quinolin-2(1H)-one; 5-Chloroacetyl-8-benzyloxy-2(1H)-quinolinone; 8-Benzyloxy-5-chloroacetyl-1,2-dihydro-2-quinolinone; 2(1H)-Quinolinone, 5-(chloroacetyl)-8-(phenylmethoxy)-; 5-(Chloroacetyl)-8-(benzyloxy)-1,2-dihydro-2-quinolinone; 63404-86-4; 8-Benzyloxy-5-chloroacetylcarbostyril
EINECS	Contact for details

Quality Control

Our 5-(Chloroacetyl)-8-(Phenylmethoxy)-2(1H)-Quinolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and contamination.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.