Description

8-Benzyloxy-1H-Quinolin-2-One is a high-purity, synthetic organic compound belonging to the quinolinone class, serving as a crucial advanced pharmaceutical intermediate. Its value lies in its role as a versatile building block for the synthesis of more complex molecules, particularly in medicinal chemistry research and development. This product is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for innovative applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Used as a core scaffold or derivatization point in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Synthesis: Serves as an intermediate in the development of new generation pesticides and herbicides, leveraging the bioactive quinolinone structure.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals, dyes, and functional materials requiring the benzyloxy-quinolinone moiety.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for fundamental organic synthesis and methodological studies.

Basic Information

Product Name	8-Benzyloxy-1H-Quinolin-2-One
CAS No.	63404-84-2
Molecular Formula	C₁₆H₁₃NO₂
Molecular Weight	251.28 g/mol
Synonyms	8-(Benzyloxy)-1H-quinolin-2-one; 8-Benzyloxy-2(1H)-quinolinone; 2-Quinolinone, 8-(phenylmethoxy)-; 8-(Phenylmethoxy)quinolin-2(1H)-one; 8-O-Benzyl-2-hydroxyquinoline; 8-Benzyloxycarbostyril; Quinolin-2-one, 8-benzyloxy-; 63404-84-2
EINECS	Contact for details

Quality Control

Our 8-Benzyloxy-1H-Quinolin-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent batch-to-batch quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.