Description

N,o-Ditosyl D-Phenylalaninol is a high-purity, protected amino alcohol derivative, specifically engineered for advanced synthetic applications. This compound serves as a critical chiral building block and protective group intermediate in the synthesis of complex organic molecules. It is essential for research and production in the pharmaceutical and fine chemical industries, where precise stereochemistry and functional group manipulation are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for peptide mimetics and enzyme inhibitors.
• Peptide Chemistry: Used in the preparation of protected amino acid derivatives for solid-phase and solution-phase peptide synthesis.
• Asymmetric Catalysis: Employed as a precursor for chiral ligands or auxiliaries in enantioselective catalytic reactions.
• Organic Synthesis: Functions as a versatile building block for constructing complex natural products and bioactive compounds.
• Protecting Group Strategy: The ditosyl groups provide orthogonal protection for the amino and alcohol functionalities, enabling selective deprotection in multi-step syntheses.
• Academic & Industrial R&D: A valuable reagent for methodological development and discovery chemistry in research laboratories.

Basic Information

Product Name	N,o-Ditosyl D-Phenylalaninol
CAS No.	63328-00-7
Molecular Formula	C23H25NO5S2
Molecular Weight	459.58 g/mol
Synonyms	D-Phenylalaninol, N,O-bis(4-methylbenzenesulfonate); (R)-2-Amino-3-phenyl-1-propanol N,O-ditosylate; N,O-Bis(p-toluenesulfonyl)-D-phenylalaninol; D-Phenylalaninol ditosylate; (R)-1-(Bis(4-methylphenyl)sulfonamido)-3-phenylpropan-2-ol; 63328-00-7; D-Phenylalaninol N,O-ditosylate
EINECS	Contact for details

Quality Control

Our N,o-Ditosyl D-Phenylalaninol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and chiral purity, and is accompanied by a detailed Certificate of Analysis (COA). We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.