Description

3-Phenyl-2-Tosyl-1,2-Oxaziridine is a specialized, high-value oxaziridine derivative, recognized for its role as a versatile electrophilic aminating and oxidizing agent in advanced organic synthesis. Its core value lies in enabling the direct introduction of nitrogen functionalities and facilitating challenging oxidation reactions under mild conditions, which is critical for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise and efficient synthetic methodologies.

Application

• Electrophilic Amination Reagent: For the direct transfer of a tosylamino (NHTs) group to carbanions, enolates, and other nucleophiles in API intermediate synthesis.
• Selective Oxidizing Agent: Utilized in the oxidation of sulfides to sulfoxides and for other selective oxygen-transfer reactions in fine chemical production.
• Building Block for Heterocycles: Serves as a key precursor in the synthesis of aziridines and other nitrogen-containing heterocyclic compounds.
• Asymmetric Synthesis: Employed in chiral auxiliary-mediated reactions for the preparation of enantiomerically enriched amines and derivatives.
• Polymer Chemistry: Used in the modification of polymers via amination or as a cross-linking agent for specialty materials.
• Academic & Industrial R&D: A critical tool for methodology development and exploring new reaction pathways in chemical research laboratories.

Basic Information

Product Name	3-Phenyl-2-Tosyl-1,2-Oxaziridine
CAS No.	63160-12-3
Molecular Formula	C15H15NO3S
Molecular Weight	289.35 g/mol
Synonyms	2-(4-Methylphenyl)sulfonyl-3-phenyloxaziridine; 3-Phenyl-2-(p-toluenesulfonyl)oxaziridine; 2-Tosyl-3-phenyloxaziridine; N-Tosyl-3-phenyloxaziridine; Oxaziridine, 3-phenyl-2-[(4-methylphenyl)sulfonyl]-; Electrophilic aminating agent TS-N; (Tosylimino)benzene oxide
EINECS	Contact for details

Quality Control

Every batch of 3-Phenyl-2-Tosyl-1,2-Oxaziridine is manufactured and tested under strict quality management protocols to ensure consistency and reliability for research and development applications. We provide comprehensive analytical data, including purity assay and impurity profile by HPLC, to support your critical work. A Certificate of Analysis (COA) detailing all specifications is available with each shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.